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There are two main differences between the cytological presentation of
the above cases. The more important is the distribution of cells. The
tumorous case presents dispersed cells while the non-tumorous case
presents compact monolayered sheets. The other less important
difference is in the degree of anisonucleosis which is less pronounced
in the case of oxyphilic adenoma than in nodular hyperplasia.
Nevertheless, the difference between the 2 cases is not absolute. In
the right case the probability of an oxyphilic tumor is in the range of
50-75%, while in the left case is in the range of 30-60%.
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