Follicular adenoma - Case 7 of a new approach

Benign hyperplastic nodule - Case 7

Microfollicular proliferation is demonstrated. Follicular cells are uniform in shape and relatively uniform in size. Because of the lack of prominent nucleoli beside a follicular tumor a hyperplastic nodule with follicular proliferation have to be considered.

This pattern corresponds to a hyperplastic nodule with microfollicular proliferation because of the presence of colloid and hyperplastic papillary clusters. Nevertheless, the cytological pattern does not exclude the possibility of follicular tumor.

The nodule presents a halo sign and perinodular blood flow, therefore this lesion is a follicular tumor with more than 90% probability.

Both the presence of a halo sign and perinodular blood flow are doubtful. In such cases the possibility of a hyperplastic nodule is greater than follciular tumor.

Taking the cytological and sonographic pattern into account, we gave a combined cytological-sonographic diagnosis of a follicular tumor with less than the average risk of carcinoma.

Taking the cytological and sonographic pattern into account, we gave a combined cytological-sonographic diagnosis of a benign follicular proliferation.