Teamwork - differential diagnostics: follicular tumor or Hashimoto's thyroiditis
Follicular adenoma - Case 34
Chronic lymphocytic thyroiditis - Case 8


The cytology corresponded to chronic lymphocytic thyroiditis. Only a few thyrocytes were found on the smear. They occurred mostly in microfollicles. One of the latter is demonstrated in the last image.


The dominant cell type is a follicular cell and the dominant structure is microfollicle. Nevertheless, there are lymphocytes and nuclear debris on the smear. Follicular tumor and lymphocytic thyroiditis have to be considered.


The nodule presents a halo sign and perinodular blood flow, therefore this lesion is a follicular tumor with more than 90% probability. Nevertheless, the extranodular part is hypoechogenic, therefore the patient harbors with great probability an autoimmune thyroiditis, too.


The thyroids are hypoechogenic so the presence of a lymphocytic thyroiditis is evident. Regarding the hyperechogenic lesion, it does not display either a halo sign or perinodular blood flow. Therefore it is unlikely that this lesion would be a follicular tumor.

Taking the cytological and sonographic pattern into account, we gave a combined cytological-sonographic diagnosis of Hashimoto's thyroiditis and suspicion of follicular tumor with less than the average risk of carcinoma.
Taking the cytological and sonographic pattern into account, we gave a combined cytological-sonographic diagnosis of a chronic lymphocytic thyroiditis.
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