Clinical presentation: A 40-year-old woman was referred for evaluation of a hypothyroidism detected on routine blood test. On ultrasound examination multiple nodules were described.

Palpation: The thyroid was firm, no nodule could be palpated.

Hormonal investigation: subclinical hypothyroidism (TSH 5.92 mIU/L, FT4 11.5 pM/l, aTPO 291 U/mL).

Ultrasonography revealed a moderately hypoechogenic thyroid containing more hypoechogenic areas. None of them fit to a nodule in a pathological sense.

Aspiration cytology was performed from one of the hypoechogenic areas and resulted in Hashimoto's thyroiditis.

Comment. Although aspiration cytology was clearly superfluous in this case, we perform aspiration if a patient was made anxious because of a previous false diagnosis of thyroid nodule.