Subacute granulomatous de Quervain's thyroiditis - Case 27. |
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Clinical data: a 37-year-old woman was referred for an evaluation of hyperthyroidism. Hyperthyroid complaints lasted for 3 weeks. She had no signs of thyroid associated ophthalmopathy.
Palpation: thyroids were moderately firm and not tender.
Functional state: hyperthyroidism (TSH 0.001 mIU/L, FT4 49.1 pM/L, FT3 9.08 pM/L).
Ultrasonography: around 60% of the thyroid was composed of hypoechogenic areas with blurred borders and decreased blood flow. After ultrasonographic examination we asked a more detailed description from the patient about her complaints. She told that at the onset of her hyperthyroid complaints her neck was tender and subfebrility was observed.
Cytological diagnosis: consistent with subacute de Quervain's thyroiditis. Follicular cells, various inflammatory cells including epitheloid cells were found on the smear.
We indicated erythrocyte sedimentation rate, CRP, aTPO and TSH-receptor antibody test with 48 mm/H, 18.7 mg/L, 1 U/mL and negative results, respectively.
Combined clinical-ultrasonographic-cytological diagnosis: benign subacute, de Quervain's thyroiditis.
We administered beta-blocking agent.
Comments.
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The extent of hyperthyroidism was in the usual range observed in Graves disease and much greater than in the case of de Quervain's thyroiditis.
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The ultrasonographic picture is almost decisive, such pattern, i.e. hypoechogenic discrete areas with blurred borders and decreased vascularization, does not occur in the hyperthyroid phase of a Graves disease. Such pattern may be observed in clinically subacute form of lymphocytic thyroiditis but infrequently.





