Clinical presentation: a 60-year-old woman was referred for an evaluation of a recurrent cystic nodule. The cyst was evacuated four times in the previous 2 years.

Cytology: resulted in benign cystic nodule. We suggested ethanol sclerotherapy instead of surgery.

Palpation: an elastic nodule in the right lobe.

Functional state: euthyroidism with TSH 0.66 mIU/L.

Ultrasonography: the thyroids were echonormal. There was a cystic nodule with echonormal solid parts in the right lobe.

Aspiration cytology: resulted in benign colloid goiter.

Six sessions of sclerotherapy were performed. We demonstrate the fourth session.

Follow-up examinations: the patient had no complaints and the nodule did not refill until the last follow-up examination performed five years after the sclerotherapy.