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Chronic lymphocytic thyroiditis - Case 20.

Nodular goiter

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Clinical presentation: a 37-year-old man was referred for an evaluation of a 'lump in the throat' feeling.

Functional state: subclinical hypothyroidism with TSH 5.01 mIU/L, FT4 13.6 pM/L.

Palpation: the left lobe was suspicious containing a small nodule.

Ultrasonography: the thyroids were moderately hypoechogenic and displayed fibrosis. There was a relatively larger hypoechogenic lesion in the central part, and other smaller ones in the dorsal part of the left lobe. The vascularization was not specific.

Aspiration cytology: resulted in Hashimoto's thyroiditis. Atypia of unknown significance; the possibility of a Hürthle-cell tumor cannot be excluded.

We told the patient that the risk of malignancy is around 5%. We offered a follow-up examination instead of a surgery. He decided to undergo the operation.

Histopathology: disclosed Hashimoto's thyroiditis. No nodules were found on a histopathological examination.

Comments:

  1. We could not decide on utrasound whether the lesion in the left lobe would be a nodule in a pathological sense. The presence of other similar areas decreased the possibility being the larger lesion a true nodule.

  2. Regarding the cytological pattern, there is no doubt that the patient has lymphocytic thyroiditis. The presence of both prominent nucleoli, grooves and inclusions raised the possibility of a Hürthle-cell tumor.

 

 

 

 

 

 

 

 

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