Clinical data: a 72-year-old woman was referred for an evaluation of a rapidly increasing nodular goiter which had a 2-month history.

Palpation: a very hard large tumor in the region of the right thyroid.

Ultrasonography: a large hypoechogenic, inhomogeneous tumor occupied almost the entire right thyroid. The left lobe was intact.

Functional state: euthyroidism (TSH 1.15 mIU/L).

Cytological report: anaplastic cancer.

Histopathology: anaplastic cancer.