Clinical data. A 31-year-old woman was referred for an evaluation of a nodular goiter known for several years. The patient noticed a slow increase in the nodule' size and she had already complaints in supine position.

Palpation: a very firm nodule in the right lobe.

Functional state: euthyroidism (TSH-level 2.81 mIU/L, FT4 10.4 pM/L, aTPO 0.4 U/mL).

Ultrasonography. There was a large, minimally hypoechogenic nodule in the right lobe. The lesion had irregular borders, presented numerous microcalcifications and increased intranodular blood flow.

Cytology resulted in suspicion of papillary carcinoma.

Histopathology disclosed papillary cancer.