Study on extrathyroidal spread of papillary carcinoma - Case 25. |
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Six years prior to present examination for 6 years (first row of images)
Clinical data: a 60-year-old woman referred for evaluation of nodular goiter. On evaluation of progressive difficulties in swallowing palsy of the left recurrent nerve and a nodular goiter was discivered.
Palpation: the left thyroid was very firm. There very enlarged lymph nodes along the left carotid artery.
Functional state: euthyroidism with TSH 3.42 mIU/L.
Ultrasonography. The thyroid was echonormal. There was a hypoechogenic nodule in the upper part of the left lobe while a hyperechogenic one in the lower two-third of the left thyroid. The former had irregular borders and presented necrotic areas. There were sevearal enlarged lymph nodes in the left side of the neck.
Cytology of the hypoechogenic nodule and one of the lymph nodes resulted in papillary carcinoma.
Histopathology disclosed a T4 stage papillary carcinoma infiltrating the capsule of the organ. 7 of the 22 removed lymph nodes contained metastatic focus.
Present examination (third row of images)
Clinical data: the patient underwent total thyroidectomy and radio-iodine therapy and thereafter she was managed in another hospital. The thyroglobulin level was between 2.9 and 5.5 ug/L in the previous years without any tendency. On the last visit a rise in the thyroglobulin level was detected (10.2 ug/L).
Palpation: a firm mass in the left thyroid bed.
Functional state: mild hyperthyroidism on daily 150 microgram levo-tiroxin with TSH 0.03 mIU/L, FT4 28.2 pM/L.
The lesion in question was located in the upper part of the left lobe.










