Clinical data: a 65-year-old woman was referred for evaluation of a thyroid nodule discovered on PET-CT. She was operated on colon carcinoma for 6 months. The PET-positive lesion was found in the right thyroid.

Palpation: the surface of the right lobe seemed to be uneven. No nodule could be palpated.

Functional state: euthyroidism (TSH 2.51 mIU/L).

Ultrasonography. The thyroid was echonormal-minimally hypoechogenic. There were multiple discrete lesions in the right lobe. None of them presented suspicious echo pattern. There was a two-chambered cyst in the left thyroid.

Cytology was performed from two lesions located in the right lobe. Cytological diagnosis: benign colloid goiter.

We performed anti-TPO test which yielded 2 U/mL.

Comment. The echo pattern resembles that of a Hashimoto's thyroiditis both because of the basic hypoechogenicity and the pattern of the lesions in the right lobe. Nevertheless, neither the cytology nor the anti-TPO level were positive for an autoimmune process.