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Graves' disease - case 121

Nodular goiter

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Right lobe, transverse scan

Right lobe, longitudinal scan

Right lobe, color Doppler mode

Right lobe, microflow imaging

Left lobe, transverse scan

Left lobe, longitudinal scan

Left lobe, color Doppler mode

Left lobe, microflow imaging

Clinical data: A 35-year-old woman was referred for a newly diagnosed hyperthyroidism. The patient had typical complaints, including elevated heart rate and weight loss.

Summary of ultrasound and laboratory data:

Date of examination

Volume of the thyroid lobes (mL)

Echogenicity index (%)

Therapy before

Results of laboratory investigations

Therapy after

Right lobe

Left lobe

TSH (mIU/L)

FT4 (pM/L)

FT3 (pM/L)

First visit

27.2

18.4
70%

Nothing

< 0.001

61.2

35.7

30 mg methimazole

5 weeks after the first visit

19.1

13.5

50%

30 mg methimazole

< 0.001

7.85

6.19

15 mg methimazole

4 months after the first visit

10.4

14.4

20%

15 mg methimazole

0.06

13.7

4.61

10 mg methimazole

9 months after the first visit

13.9

12.0

10%

10 mg methimazole

1.98

8.11

-

5 mg methimazole

12 months after the first visit

10.1

11.3

< 10%

5 mg methimazole every other day

4.97

10.1

-

Nothing

 

Comment.

This is the typical course of a non-relapsing Graves' hyperthyroidism. As the hormone results improve, both the size of the initially enlarged goiter and the degree of hypoechogenicity decrease.

 

 

 

 

 

 

 

 

 

 

 

 

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