Graves' disease - case 799 |
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Right lobe, transverse scan
Right lobe, longitudinal scan
Right lobe, color Doppler mode
Right lobe, microflow imaging
Left lobe, transverse scan
Left lobe, longitudinal scan
Left lobe, color Doppler mode
Summary of ultrasound and laboratory data:
Date of examination |
Volume of the thyroid lobes (mL) |
Echogenicity index (%) |
Therapy before |
Results of laboratory investigations |
TSAb (U/L) (normal value < 1.5) |
Therapy after |
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Right lobe |
Left lobe |
TSH (mIU/L) |
FT4 (pM/L) |
FT3 (pM/L) |
|||||
7 months after delivery |
8.3 |
6.6 |
70% |
Nothing |
0.01 |
17.7 |
7.16 |
1.5 |
Nothing |
9 months after delivery |
12.9 |
12.4 |
25% |
Nothing |
< 0.001 |
51.6 |
6.90 |
6.0 |
20 mg methimazole |
11 months after delivery |
19.5 |
15.9 |
80% |
20 mg methimazole |
33.7 |
3.83 |
- |
- |
10 mg methimazole |
14 months after delivery |
11.9 |
8.7 |
20% |
10 mg methimazole |
5.91 |
12.5 |
- |
- |
5 mg methimazole |
20 months after delivery |
12.8 |
11.8 |
15% |
5 mg methimazole |
2.08 |
12.6 |
- |
0.1 |
Nothing |
First examination - additional clinical data: A 27-year-old woman was referred for evaluation. She gave birth seven months ago. In the following months, she experienced significant weight loss, sweating, and a high heart rate. Symptoms significantly diminished by the time of the first study.
Second examination - additional clinical data: The patient's previous symptoms recurred two weeks before the study.
Comments.
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Based on the clinical symptoms, it is assumed that the patient already had spontaneously improving hyperthyroidism in the months after delivery.
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Neither clinical nor hormonal course is characteristic of post partum thyroiditis but is of Graves' disease.
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This is the typical course of a Graves' hyperthyroidism which does not relapse within a year. As the hormone result improves, both the size of the initially enlarged goiter and the degree of hypoechogenicity decrease.