Differential diagnostics of oxyphilic lesions - table 1
Benign hyperplastic nodule - case 52
Oxyphilic adenoma - a new approach - case 4

Oxyphilic ells are predominantly found in small cohesive groups. In the left case microfollicles can be seen, too and nuclei contain prominent nucleoli. On this presentation the left case may be either an oxyphilic tumor or a hyperplastic nodule.
As regards the right case, a lymphocytic thyroiditis is evident on the smear which explains the atypia and mild pleomorphism. We have no reason to suggest an oxyphilic tumor solely on the cytological pattern.

Taking the ultrasound presentation into account deeply alters our opinion. The nodule in the left case presents neither a halo nor a perinodular lood flow, therefore the chance for a follicular type tumor is negligible.
On the other hand, in the right case a solitary nodule occupies almost the entire lobe, the lesion displays both halo and perinodular blood flow, therefore the most likely diagnosis on ultrasound presentation is a follicular type tumor.

mask