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Subacute granulomatous thyroiditis - case 918

Nodular goiter

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First examination (1st and 4th rows of images):

Clinical presentation: A 34-year-old woman was referred for an evaluation of neck complaints. Neck pain and fever started 2 month ago and lasted for 3 weeks. Then complaints suggesting hyperthyroidism have developed. The neck complaints have decreased. The body temperature has normalized.

Palpation: The right lobe was tender and hard on palpation.

Functional state: hyperthyroidism with TSH 0.01 mIU/L and FT4 27.2 pM/L, CRP 12.8 mg/L (normal value 0-4.8), TSAb 0 U/L.

Ultrasonography: The thyroid was echonormal and presented hypoechogenic areas with ill-defined borders. The vascularization was average.

Aspiration cytology was performed from right thyroid and resulted in subacute, granulomatous, de Quervain's thyroiditis.

Non-steroid anti inflammatory drug was administered.

Follow-up examination 3 months later (2nd row of images):

Clinical presentation: The complaints of the patient ceased.

Palpation: The thyroid was not tender, both lobes were firm.

Functional state: hypothyroidism with TSH 2.98 mIU/L and FT4 7.56 pM/L. CRP 1.9 mg/L.

Ultrasonography: The proportion of hypoechogenic areas has decreased. The vascularization became normal.

Follow-up examination 11 months later (3rd row of images):

Clinical presentation: The patient had no complaints.

Palpation: no abnormality.

Functional state: euthyroidism with TSH 1.09 mIU/L, and FT4 17.1 pM/L.

Ultrasonography: The thyroid was echonormal with several small minimally hypoechogenic areas. The vascularization was less than the average.

 

 

 

 

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