| Increasing
the
ratio of oxyphilic cells to lymphocytes, increasing the risk of an
underlying oxyphilic cell tumor. Other properties which have to be
taken into consideration in cytologic differential diagnostic are the
presence of even a few lymphocytes within oxyphilic groups, nuclear
debris and prominent nucleoli. Nuclear debris are found in both of the
examples presented here. In the first case, the lack of lymphocytes,
while in the second case, the presence of nucleoli may lead to false
diagnosis of a tumor. Although considering all cytological signs,
lymphocytic thyroiditis is more probable than Hürthle-cell tumor,
even an experienced cytopathologist is in a difficult situation if he
does not get help to make a correct decision analysing such a
pattern. Clinical data (hypothyroidism and or elevated aTPO level) and
the ultrasound pattern in combination with cytological details can lead
to a correct diagnosis . |
