|
Compare the left
and right images. Histologically verified Hashimoto's thyroiditis is
demonstrated on the left, while histologically proven coexisting
papillary cancer and Hashimoto's thyroiditis on the right. The
cytological pattern is very similar in these cases. Inclusions which
are the most specific signs of papillary cancer are found on the left
smears, in the case of Hashimoto's thyroiditis. Lesions with oxyphilic
metaplasia mean the most important limitation of nuclear inclusion as a
diagnostic tool. In contrast with non-metaplastic cells, which only
rarely contain inclusion, in the case of oxyphilic cells the presence
of
inclusion is absolutely not an infrequent finding. Although it was not
a great task to avoid false diagnosis of papillary cancer because the
patient had no nodule, the example demonstrated here emphasizes the
need for a new approach in the diagnosis of thyroid diseases. Even in
less equivocal cases, the cytolopathologist has to give the diagnosis
of
suspicion of papillary cancer, while if we consider other facts, most
importantly the result of ultrasound, the patient will be able to avoid
an
absolutely unnecessary surgical procedure. As a result, we prefer to
give a combined sonographic-clinical-cytologic diagnosis in such cases.
|