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We had to consider the previous radioiodine therapy of the patient to
interpret the cytology correctly. Follicular cells display extreme
anisonucleosis and even pleomorphism can be observed. Thyrocytes occur
mostly in monolayered sheets. Note vacuolization. The cytological
pattern corresponds to a benign lesion with atypia caused by the
previous radioiodine therapy.
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The cytological pattern is suspicious for follicular carcinoma.
Follicular cells are elongated and pleomorphic forms can be found, as
well. Microfollicles including abortive forms predominate the smear.
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The nodule presents a halo sign and perinodular blood flow, therefore
this lesion is a follicular tumor with more than 90% probability.
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The nodule does not display a halo sign and the presence of perinodular
blood flow is doubtful. The sonographic presentation is suspicious
because of the irregular borders.
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Taking the cytological and sonographic
pattern into account, we gave a combined cytological-sonographic
diagnosis of a follicular tumor.
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Taking the cytological and sonographic
pattern into account, we gave a combined cytological-sonographic
diagnosis of a follicular tumor with greater than the average risk of
malignancy.
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