Role of the teamwork - follicular proliferation
Benign hyperplastic nodule - Case 9
Follicular adenoma - Case 9


This is not a simple microfollicular pattern, because normofollicles predominate the smear. Moreover follicular cells do not contain prominent nucleoli. Nevertheless, the cytological picture is suspicious for follicular tumor.


This is also not a classical microfollicular pattern. Thyrocytes are partly found in hyperplastic papillary fragments. Nevertheless, first of all in low power field the pattern raises the possibility of follicular tumor.
Both thyroids contained large nodules with calcified capsule. Neither a halo sign nor perinodular blood flow was found.

No halo sign can be found on gray scale mode. However, there is perinodular blood flow on Doppler mode. Solitary nodules with this pattern are follicular tumors in more than 90% of cases.

Taking the ultrasound pattern into account, we could avoid a false diagnosis of follicular tumor, our combined cytological-sonographic diagnosis was benign follicular proliferation. Final histopathology disclosed benign hyperplastic nodule.
Taking the sonographic and the cytological pattern into account our diagnosis was follicular tumor.
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