Role of the teamwork in diagnosing papillary carcinoma
Papillary cancers - Case 66

Two cell populations are demonstrated. Firstly, small pycnotic nuclei which predominate the smear. Secondly, there are a few enlarged atypical cells with abundant cytoplasm and prominent nucleoli.

Ultrasonography of the right thyroid

The sonographic pattern is suspicious because the nodule contains hyperechogenic granules and has blurred borders.

Ultrasonography of the right side of the neck

There is enlarged lymph node containing microcalcifications and lacking regular hilum.


The cytological findings were not enough to raise the possibility of malignancy, they corresponded to AUS category of Bethesda system. Taking the sonographic pattern into account, a combined sonographic-cytological diagnosis could raise the possibility of a thyroid carcinoma. It is worth mentioning that 9 aspirations occurred in this patient at two different occasions and only one smear contained a few suspicious cells. It seems possible that if we followed the Bethesda protocol, atypical cells would be missed later in the course and longer delay would occur in the correct therapy.

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