Clinical presentation: a 45-year-old woman with the suspicion of hyperthyroidism.

Palpation: no abnormality.

Functional state: euthyroidism (TSH 2.17 mIU/L, FT4 13.1 pM/L).

Ultrasonography: a moderately hypoechogenic nodule in the right lobe.

Cytological report: Hürthle-cell tumor.

Histopathology: disclosed nodular colloid goiter with degenerative changes.

Comment: the lack of dissociating cells stands against the possibility of Hürthle-cell tumor, while the presence of prominent nucleoli argues for that.