Clinical presentation: A 20-year-old woman was referred for an evaluation of a suddenly developed thyroid nodule.

Palpation: an elastic large nodule in the left lobe.

Functional state: euthyroidism (TSH 1.19 mIU/L).

Ultrasonography: There was a cystic nodule in the left lobe. The solid part of the nodule contained microcalcifications and displayed intranodular vascular pattern.

FNA was benign, cystic-colloid goiter.

The nodule was refilled next day after the evacuation. Surgery was performed.

Histopathology: benign hyperplastic nodule with degenerative changes.