Clinical presentation: a 38-year-old woman was referred for an evaluation of a nodule detected on a physical examination.

Palpation: a firm nodule in the right lobe.

Functional state: euthyroidism (TSH 0.75 mIU/L).

Ultrasonography:  the thyroids were echonormal. There was a moderately hypoechogenic nodule displaying both perinodular and intranodular blood flow.

Cytology: resulted in benign colloid goiter with follicular proliferation.

The nodule later increased in size further and two years after the initial examination the patient underwent surgery.

Histopathology: benign, hyperplastic nodular goiter.