Characteristic cytological properties

Benign hyperplastic nodule - Case 17


Colloid in the background. Hyperplastic papillary fragments and naked pycnotic hyperchromatic dissociated nuclei - these are the most important cytological sign of a benign colloid goiter.


Benign hyperplastic nodule - Case 55

There is no colloid in the background. Moreover, there is a microfollicular growth pattern and follicular cells display oxyphilic changes. Nevertheless the hyperplastic papillary structures and the lack of prominent nucleoli and nuclear atypia stands against the possibility of a thyroid tumor.
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